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Thrombosis Topics, Prediction Indicators

https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/602172

https://www.webmd.com/a-to-z-guides/partial-thromboplastin-time-test#1

webmd.com/a-to-z-guides/partial-thromboplastin-time-test#1(opens in a new tab)

Partial Thromboplastin Time, Activated 

Updated: Jul 30, 2019 

  • Author: Muhammad Bader Hammami, MD; Chief Editor: Eric B Staros, MD

Reference Range

Partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) are used to test for the same functions; however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy.

The reference range of the aPTT is 30-40 seconds. [1, 2, 3]

The reference range of the PTT is 60-70 seconds.

In patients receiving anticoagulant therapy, the reference range is 1.5-2.5 times the control value in seconds.

Critical values that should prompt a clinical alert are as follows:

  • aPTT: More than 70 seconds (signifies spontaneous bleeding)

  • PTT: More than 100 seconds (signifies spontaneous bleeding)

https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/602172

https://www.webmd.com/a-to-z-guides/partial-thromboplastin-time-test#1

webmd.com/a-to-z-guides/partial-thromboplastin-time-test#1(opens in a new tab)

Partial Thromboplastin Time, Activated 

Updated: Jul 30, 2019 

  • Author: Muhammad Bader Hammami, MD; Chief Editor: Eric B Staros, MD

Reference Range

Partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT) are used to test for the same functions; however, in aPTT, an activator is added that speeds up the clotting time and results in a narrower reference range. The aPTT is considered a more sensitive version of the PTT and is used to monitor the patient’s response to heparin therapy.

The reference range of the aPTT is 30-40 seconds. [1, 2, 3]

The reference range of the PTT is 60-70 seconds.

In patients receiving anticoagulant therapy, the reference range is 1.5-2.5 times the control value in seconds.

Critical values that should prompt a clinical alert are as follows:

  • aPTT: More than 70 seconds (signifies spontaneous bleeding)

  • PTT: More than 100 seconds (signifies spontaneous bleeding)

Fast Facts - Join the Fight

  • Most people have never heard of Factor V Leiden.
  • A lot of people carry the genetic mutation and a few people develop blood clots that are related to Factor V Leiden.
  • Do you know someone who has suffered a deep vein thrombosis, pulmonary embolism, or other type of venous blood clot? In many cases, those blood clots were caused by issues relating to Factor V Leiden.
  • A large number of people live every day with complications caused by blood clots.
  • Sadly, the Centers for Disease Control (CDC) estimates that 274 people die each day or over 100,000 each year as a result of blood clots.
  • If the person had known they carried the Factor V Leiden gene mutation, in many cases some very simple steps taken beforehand may have saved their life.

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